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Opioids are prescribed for pain relief; most recognizable are morphine, hydrocodone, oxycodone, and fentanyl. Opioids also include the illegal drug, heroin. Opioid use disorder (OUD) (to include prescription drugs and heroin) is the fastest growing substance use problem in the nation. During 2008-13, 4.7% of U.S. residents ages 12 and older reported using non-medical opioids in the past year.